METHODS AND OBJECTS OF CHEMICAL ANALYSIS

An international journal devoted to all aspects of analytical chemistry

ISSN 2413-6166 (Online), ISSN 1991-0290 (Print)

Ukr | En

Electrochemical Evaluation of Catalytic Effect of Aluminum in Oxidation the Paracetamol in Human Blood

Hayat EL Ouafy^†, Tarik EL Ouafy*^‡, Mustapha Oubenali^†, Aziz EL Haimouti^‡, Ahmed Gamouh^†, Mohamed Mbarki^†

* Corresponding author

^† Team of Analytical and Computational Chemistry, Nanotechnology and Environment, Department of Chemistry and Environment, Faculty of Science and Technics, Sultan Moulay Slimane University, Beni Mellal, Morocco;
^‡ Team of Analytical and Computational Chemistry, Nanotechnology and Environment, Department of Physics and Chemistry, Polydisciplinary Faculty of Khouribga, Sultan Moulay Slimane University, Beni Mellal, Morocco.

*e-mail: tarikelouafy@gmail.com

Methods Objects Chem. Anal., 2021, 16(3), p. 162-168

https://doi.org/10.17721/moca.2021.162-168

The article is distributed under open access Creative Commons Attribution License CC BY 4.0.

download the article

download the references

Abstract

The reactivity of paracetamol (Pa) using the carbon paste electrode (CPE) modified by the aluminum (CPE-Al) was reported. The working electrode was prepared by mixing the aluminum with the carbon powder. The optimal potential window was selected from -1.7 V to 1.7 V. The effect of parameters such as pH, scan rate, accumulation time and concentration were affected by cyclic voltammetry (CV) and square wave voltammetry (SWV). The optimal preconcentration time is 8 minutes. The reactivity of Pa on the electroanalysis detector was characterized by the appearance of the anodic peak at 0.25 V in a solution of sodium sulfate (0.1 M, pH 7). The calculated limits of detection and quantification have been 8.28·10^-9 and 2.74·10^-8 mol L^-1, respectively. Then relative standard deviation (RSD) at 2.0·10^-5 mol L^-1 Pa concentration was 4.08 % for nine repetitions. The analytical application was carried out in the detection of Pa in human blood with satisfying results.

Received: January 20, 2021; Accepted: May 15, 2021; Published online: October 05, 2021

Keywords: electroanalysis, electrode, paracetamol, cyclic voltammetry, square wave voltammetry, human blood

Article language: En.

Publisher: Taras Shevchenko National University, Kiev Ukraine

(Analytical chemistry department at Taras Shevchenko National University, 64 Vladimirskaya STR., Kiev, 01601 UKRAINE)
analysis@univ.kiev.ua, www.univ.kiev.ua, +380 (44) 2393444

The journal is indexed in SCOPUS and Web of Science

The journal website: www.moca.net.ua

The articles in this journal are licensed under CC BY 4.0