Electrochemical Method for Determination of Cyclamate using 12-Molybdophosphoric Acid O.V. Volnyanska†, O.V. Labyak†, M. Ye. Blazheyevskiy‡, O.A. Brizitskiy*‡, V.I. Tkachz†
	* Corresponding authors † Ukrainian State University of Chemical Technology, 8 Gagarіna av., Dnipro, 49005, Ukraine; ‡ National University of Pharmacy, 53 Pushkinska str., Kharkiv, 61002, Ukraine; *e-mail: alexchemis@rambler.ru
	Methods Objects Chem. Anal., 2018, 13(1), p. 29-34 https://doi.org/10.17721/moca.2018.29-34
	Buy Article: 2 USD plus tax DOI Id	preview the article

Abstract

Procedure for quantitative determination of the Cyclamate (E-952) by a direct ionometric method with ionselective electrode (ISE) has been developed. The electrode is reversibly selective to the product of Cyclamate decomposition - cationic complex of cyclohexene sulfamic acid with barium ions. Electrochemical sensor with Polyvinylchloride membrane having an ionic associate of cyclohexene sulfamic acid with barium ions and 12-molybdophoshoric acid as ion exchanger is proposed. It has been experimentally studied the influence of membrane composition and preparation procedure on electroanalytical characteristics of electrode, such as: electrode function, slope, linearity range, pH. The possibility of quantitative determination of the cyclamate in the food additive E-952 and other industrial products using the developed ISE is demonstrated. The method meets all the requirements of modern analysis - simple, safe and inexpensive, sufficient precise, sensitive and selective. Sensor response time doesn’t exceed 50 s, and long membrane life (35-55 days) allows to perform analysis without replacement of the membrane. By means of sensor it is possible to determine Cyclamate in solutions containing 10-5 ‒ 10-2 mol/l with relative standard deviation less than 2.3 %. ( x- μ) 100 % / μ < RSD.

Keywords: cyclamate; ion-selective electrode (ISE); 12 -molybdophosphoric acid; ionometry; sensor membranes

Article language: En